Key result
Dynamic contrast-enhanced (DCE) magnetic resonance imaging is a promising noninvasive tool to quantitatively characterize atherosclerotic plaque inflammation and monitor therapeutic response.
DCE-MRI is a promising noninvasive imaging modality for the quantitative assessment of atherosclerotic plaque inflammation.
Does not support routine clinical use of DCE-MRI; leaves open its validation in prospective trials for plaque monitoring.
Inflammation plays an important role in atherosclerosis. Given the increasing interest in using in-vivo imaging methods to study the physiology and treatment effects in atherosclerosis, noninvasive intraplaque inflammation quantitative method is needed. Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) has been proposed and validated to quantitatively characterize atherosclerotic plaque inflammation. Recent studies have optimized the imaging protocol, pharmacokinetic modeling techniques. All of these technical advances further promoted DCE-MRI to clinical investigations in plaque risk assessment and therapeutic response monitor. Although larger clinical studies are still needed, DCE-MRI has been proven to be a promising tool to reveal more about intraplaque inflammation by in vivo quantitative inflammation imaging.
No takes yet. Share an insight, caveat, or question.
Chen et al. (2013) conducted an editorial in Atherosclerosis. Dynamic contrast-enhanced (DCE) MRI was evaluated. Dynamic contrast-enhanced (DCE) magnetic resonance imaging is a promising noninvasive tool to quantitatively characterize atherosclerotic plaque inflammation and monitor therapeutic response.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: