Differential (δ A), second derivative (D2) and differential second derivative (δ D2) ultraviolet spectrophotometric methods have been described for the quantitiative estimation of clonazepam, diazepam and medazepam in pharmaceutical formulations such as drops, tablets and capsules. Interferences due to excipients and diluents are thereby avoided. Accuracy of the analyses with the proposed procedures is significantly greater than the conventional spectrophotometric and official methods.
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Abdel‐Hamid et al. (1984) studied this question.
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