In the course of screening for new antifungal agents from fermentation broths, we have discovered two novel antifungal compounds, Sch 47554 (1) and Sch 47555 (2), which are structurally related to the angucycline group of antibiotics1} which includes aquayamycin and saquayamycins. Both compounds were produced by a strain of Streptomyces sp. SCC-2136 (ATCC 55186) isolated from a soil sample collected in Edmonton, Alberta, Canada. In this paper we wish to report the production, isolation, and structure elucidation of 1 and 2 using spectroscopic methods as well as chemical degradations.
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Chu et al. (1993) studied this question.
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