Why the study?
Does isoflurane alter the membrane responses of human sympathetic ganglion neurons in vitro?
Does isoflurane alter the membrane responses of human sympathetic ganglion neurons in vitro?
This study demonstrates for the first time that human sympathetic ganglion neurons can be studied in vitro, revealing that isoflurane reduces repetitive spike firing, which may contribute to clinical hypotension.
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May link isoflurane to hypotension via sympathetic suppression; leaves open confirmation in human neurons.
Puil et al. (1988) studied this question.
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