Key result
Phylogenetic analysis of 32 Taiwanese avian infectious bronchitis virus strains revealed two distinct lineages and evidence of intergenic recombination between the S1 and N genes.
Taiwanese IBV strains form distinct local clusters with evidence of intergenic recombination, suggesting local strains should be used for vaccine development.
May support local Taiwanese IBV strains in regional vaccines; leaves open functional validation of recombination effects.
The disease caused by infectious bronchitis virus (IBV) produces great economic for the poultry industry. The purpose of this study is to investigate the molecular epidemiology of IBV in Taiwan. An old IBV strain isolated in 1964 and another 31 strains isolated from 1991 to 2003 were selected for N-terminal S1 gene analysis. Based on their phylogenetic tree, 13 strains were selected for sequencing the entire S1 and partial nucleocapsid (N) genes. The results indicated that Taiwanese IBV strains could be divided into two distinct lineages, Taiwan Group I and Taiwan Group II, with one Massachusetts strain and one Chinese strain. No recombination was found between H120 and the Taiwanese strains in the S1 gene. However, the S1 gene showed a noticeably higher divergence than the N gene. The phylogenetic trees constructed from the S1 and N genes indicate that intergenic recombination has occurred. Since most local strains are in Taiwanese clusters, developing vaccines from local strains is necessary for IBV control in Taiwan.
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Huang et al. (2004) studied Avian infectious bronchitis virus (IBV) (n=32). S1 and N gene analysis was evaluated on Phylogenetic lineage and recombination. Phylogenetic analysis of 32 Taiwanese avian infectious bronchitis virus strains revealed two distinct lineages and evidence of intergenic recombination between the S1 and N genes.
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