Intramolecular Hydroamination of Unactivated Alkenes with Secondary Alkyl- and Arylamines Employing [Ir(COD)Cl]2 as a Catalyst Precursor

Commercially available [Ir(COD)Cl](2) is an effective precatalyst for the intramolecular hydroamination of a range of unactivated alkenes with pendant secondary alkyl- or arylamines, at relatively low loadings (typically 0.25-5.0 mol % Ir) and without the need for added ligands or other cocatalysts.