Key result
Ultrasound-guided thrombin injection achieved 100% technical success and clinical efficacy in obliterating refractory pseudoaneurysms following thyroid biopsy, with no major complications.
Why the study?
Iatrogenic pseudoaneurysm is a rare but potentially fatal complication of thyroid biopsy, but a standard management strategy has not yet been established.
Does ultrasound-guided thrombin injection safely and effectively treat pseudoaneurysms arising after thyroid biopsy?
Observational (n=7,256)
No
Does ultrasound-guided thrombin injection safely and effectively treat pseudoaneurysms arising after thyroid biopsy?
Ultrasound-guided thrombin injection is an effective and safe minimally invasive method for managing rare pseudoaneurysms following thyroid biopsy.
May support TI for post-biopsy pseudoaneurysms; leaves open need for prospective trials before routine use.
Iatrogenic pseudoaneurysm is a rare but potentially fatal complication of a thyroid biopsy. However, a standard management strategy has not yet been established. We aimed to evaluate the efficacy and safety of ultrasound (US)-guided thrombin injection (TI) for thyroid pseudoaneurysms. This retrospective study included 7256 patients who underwent thyroid biopsy and TI from January 2020 to January 2024. The technical success, clinical efficacy, and complication rates were evaluated. A total of 0.1% (7/7256) of pseudoaneurysms developed after thyroid biopsy. Except for 1 case that showed obliteration with manual compression, the remaining 6 refractory aneurysms (0.08%) were managed with US-guided TI. All cases (100%) were successfully occluded with US-guided TI. No major complications were observed. One patient (16.7%) developed transient loss of consciousness, which spontaneously resolved within a few seconds. US-guided TI is an effective, relatively safe, and minimally invasive method for managing pseudoaneurysms after thyroid biopsy.
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Ham et al. (2024) conducted an observational in Iatrogenic pseudoaneurysm after thyroid biopsy (n=7,256). Ultrasound-guided thrombin injection was evaluated on Technical success and clinical efficacy (complete obliteration of the pseudoaneurysm). Ultrasound-guided thrombin injection achieved 100% technical success and clinical efficacy in obliterating refractory pseudoaneurysms following thyroid biopsy, with no major complications.
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