Key result
WHO Class III maternal cardiac disease was associated with significantly lower neonatal birth weights and higher preterm delivery rates compared to lower risk classes.
Observational (n=383)
Higher WHO risk classes in pregnant women with cardiac disease are associated with worse obstetric outcomes, including lower birth weights and higher preterm delivery rates.
Adverse outcomes appear common in cardiac pregnancies; leaves open optimal risk stratification and management strategies.
AIM: To evaluate the pregnancy outcomes of women with heart disease. MATERIALS AND METHODS: In this retrospective study, 383 pregnant women with cardiac diseases were examined. The cases were classified according to the World Health Organization (WHO) classification. The distribution of the cases according to class, congenital heart diseases, mean birthweight, mean gestational week at delivery, type of delivery [cesarean section (CS) or vaginal delivery], and cardivascular events (during pregnancy and puerperium) were evaluated. RESULTS: Of the 383 patients, 25 were in Class I; 39, Class II; 255, Class II or III; 31, Class III; and 33, Class IV cardiac diseases. The neonatal birth weights were significantly lower in Class III than in Classes II, and II or III. The preterm delivery rate was higher in Class III than in the other classes. Delivery was performed by CS due to cardiac indications in the high-risk classes, however, only obstetric indications were considered in the low-risk classes. Only one case of maternal death occurred during the postpartum period, in a patient with Eisenmenger's syndrome. DISCUSSION: Cardiovascular diseases are an important cause of mortality and morbidity in pregnancy. The adverse impact of cardiovascular disorders on pregnancy outcomes should be the main concern during the management of these women.
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Aydın et al. (2018) conducted an observational in Maternal cardiac diseases (n=383). Maternal cardiac disease vs. Between WHO classes was evaluated on Pregnancy outcomes (birthweight, gestational week, delivery type, cardiovascular events). WHO Class III maternal cardiac disease was associated with significantly lower neonatal birth weights and higher preterm delivery rates compared to lower risk classes.
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