Key result
Maternal heart disease was associated with neonatal adverse events in 35% of pregnancies, with NYHA class (P=0.001) and prior cardiac events (P<0.001) serving as significant predictors.
Why the study?
Pregnancy-associated cardiocirculatory changes may threaten maternal outcome and have fetal and neonatal implications, prompting the need to assess the impact of maternal heart disease and identify predictors of adverse neonatal outcomes.
What are the predictors of adverse neonatal outcomes in pregnant women with heart disease?
Cohort (n=100)
No
What are the predictors of adverse neonatal outcomes in pregnant women with heart disease?
In pregnant women with heart disease, adverse neonatal outcomes occur in 35% of cases and are significantly predicted by maternal NYHA class, left heart obstruction, prior cardiac events, and the need for cardiac medications.
Answers are grounded in this paper and cite their sources.
Neonatal complications affect over one-third of pregnancies with maternal heart disease; leaves open need for validated risk stratification in prospective cohorts.
BACKGROUND ‐associated cardio circulatory changes- primarily, increase in heart rate, volume, and cardiac output, as well as reduction in systemic vascular , may threaten maternal outcome; which in turn has foetal and neonatal . We wanted to assess the impact of heart disease during pregnancy, the neonatal outcomes of pregnancies in women with heart disease and predictors of adverse neonatal outcomes. of all pregnant women with documented heart disease who were admitted a rural tertiary centre in Kerala over a period of 3 years was collected. Patients medical termination of pregnancy were excluded from the study. The outcomes of pregnancies in 100 women with heart disease, were . 100 mothers with heart disease, neonatal adverse events complicated 35% of . In 31% cases, the babies were small for gestational age. There were 10 cases with Respiratory Distress Syndrome, 7 preterm babies and 6 cases with APGAR scores. The live birth rate for pregnancies that continued beyond 20 was 96%. NYHA class is a statistically significant predictor of neonatal (p value 0.001). 14 out of 28 pregnancies with left heart obstruction had a complication, which was statistically significant (p value 0.050). Previous of cardiac events was present in 9 cases and 88.9% of these patients a neonatal event (p value 0.000). The requirement of cardiac was also a significant predictor of neonatal events (p values- 0.004). management of pregnant woman with heart disease requires a team work for a good outcome. Early risk stratification, good care and early recognition of complications are important measures to the prognosis in these women.
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Sapna et al. (2019) conducted a cohort in Maternal Cardiac Disease (n=100). Maternal heart disease and clinical risk factors was evaluated on Neonatal adverse events. Maternal heart disease was associated with neonatal adverse events in 35% of pregnancies, with NYHA class (P=0.001) and prior cardiac events (P<0.001) serving as significant predictors.
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