Why the study?
Does maternal cardiac disease or digoxin administration affect the duration of pregnancy, labour, birth weight, or Apgar score?
Population
372 pregnant women (122 with cardiac disease, 250 controls)
Comparison
Maternal cardiac disease and digoxin… vs Pregnant women without cardiac disease (controls)
Design
Cohort
Authors
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May support closer fetal growth monitoring in maternal cardiac disease; leaves open digoxin effects pending prospective confirmation.
Does maternal cardiac disease or digoxin administration affect the duration of pregnancy, labour, birth weight, or Apgar score?
Maternal cardiac disease is associated with lower birth weights and earlier delivery in multiparous women, whereas digoxin use does not significantly impact these perinatal outcomes.
Ho et al. (1980) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: