Population
Cat experimental model
Comparison
Prostaglandin F2alpha vs Spasmogenic platelet factor
Design
Preclinical
Authors
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PGF2α unlikely primary physiological spasmogen; leaves open identification of the true platelet-derived factor in animal vasospasm models.
Prostaglandin F2alpha is unlikely to be the primary physiological spasmogenic platelet factor due to the high concentrations required for arterial spasm and differing enzymatic susceptibility.
Kapp et al. (1976) studied this question.
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