Why the study?
Does a computer-controlled propofol infusion system without nitrous oxide allow safe induction of anaesthesia in a patient with an undrained pneumothorax?
Does a computer-controlled propofol infusion system without nitrous oxide allow safe induction of anaesthesia in a patient with an undrained pneumothorax?
Answers are grounded in this paper and cite their sources.
Computer-controlled propofol infusion without nitrous oxide may be a safe alternative for induction of anaesthesia in patients with undrained pneumothorax where positive pressure ventilation must be avoided initially.
A patient who required pleurectomy had a 30% pneumothorax when she was presented for anaesthesia. She had refused to have this drained, and it had not responded to conservative management. She was anaesthetised using a computer-controlled propofol infusion system, without the use of nitrous oxide, and a chest drain was inserted before the institution of positive pressure ventilation. This technique reduces the hazards associated with general anaesthesia in the presence of an undrained pneumothorax. It may be a safe alternative method of induction of anaesthesia in other conditions in which positive pressure ventilation must be avoided, such as bronchopleural fistula.
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Crofts et al. (1991) studied this question.
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