A two-stage topical treatment regime, AgF followed by SnF2, was used as a caries preventive measure in newly-erupted first permanent molars in a group of children. Another group of children, from similar geographic and socio-economic backgrounds was treated by a one stage topical application of SnF2 only. The teeth treated were observed at six-monthly intervals for a period of 18 months, and showed a significantly higher incidence of caries developing when treated with SnF2 only.
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Eleonore Green (1989) studied this question.
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