Why the study?
Does restriction of the aortic root by a ligature prevent diastolic valvular incompetence in models of aortic sinus dilatation?
Population
Model experiments of aortic sinus dilatation
Design
Preclinical
Authors
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May inform root-restriction strategies in experimental AI; hypothesis-generating for human aortopathy, with no practice change warranted.
Does restriction of the aortic root by a ligature prevent diastolic valvular incompetence in models of aortic sinus dilatation?
In experimental models, aortic incompetence due to sinus dilatation is caused by insufficient valvular elongation and can be aborted by mechanical restriction of the aortic root.
Bellhouse et al. (1973) studied this question.
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