Why the study?
Pericardial involvement is rare in non-Hodgkin lymphoma, though 20% of patients may present with pleural effusion.
Non-Hodgkin lymphoma can rarely present as recurrent pleuropericardial effusion and can be successfully managed with standard chemotherapy.
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Recurrent pleuro-pericardial effusion may indicate occult NHL; case reports leave open systematic screening recommendations.
Non-Hodgkin lymphoma is a lymphoproliferative disorder usually affecting lymphoid organs. 20% patients with non-Hodgkin lymphoma may present with pleural effusion but pericardial involvement is rare. Pleural & pericardial effusion in lymphoma are usually due to direct seeding of malignant cells or by obstruction to the lymphatic drainage of pleura & pericardium. We report a case of non-Hodgkin lymphoma presenting as recurrent pleuro-pericardial effusion. A middle aged male with chief complaints of progressive dyspnea, palpitation & generalized pufness for past 2 months was found to have bilateral pleural effusion, pericardial effusion, ascites & generalized lymphadenopathy. Right supraclavicular lymph was node was evaluated using FNAC & excisional biopsy. Pleural & pericardial uids were analyzed. He was diagnosed as Non-Hodgkin lymphoma and started with Rituximab, Prednisolone, Cyclophosphamide, Vincristine & Doxorubicin. Patient improved on subsequent follow up
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Panda et al. (2023) studied this question.
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