Continuous exposure by inhalation to 200‐300 ppm of benzene, for 4‐7 hours daily, 5 days weekly, causes the onset of zymbal gland carcinomas in male and female Sprague‐Dawley rats. This report deals with the results 86 weeks after the start of the experiment. At this stage 227 out of 269 treated animals and 256 out of 307 controls are still alive. The surviving animals will be kept under observation until spontaneous death occurs.
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Maltoni et al. (1982) studied this question.