Treatment of infection caused by Borrelia burgdorferi sensu lato

Borrelia burgdorferi sensu lato (Bbsl) infections, which are transmitted by Ixodes ticks, cause a wide variety of clinical manifestations and are of public health importance in parts of North America, Europe and Asia. A literature review of pertinent articles published up untill July 6th 2010 was performed on the use of antimicrobials in the treatment and prevention of Bbsl infections. The clinical outcome with 10-28 days of antibiotic treatment is generally excellent, but in view of the experience with other infections, future studies might address whether the duration of antibiotic therapy could be shortened.