A novel variant of the asymmetric oxidation of prochiral thioethers yields chiral sulfoxides with selectivities of up to 98% de. The thioether is first coordinated to an enantiomerically pure auxiliary and then oxidized in the coordination sphere with dimethyldioxirane [Eq. (a)]. Smooth decomplexation is achieved with Nal.
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Schenk et al. (1994) studied this question.
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