Key result
Methylphenidate use is linked to ~61% higher arrhythmia risk during the first two treatment months.
What to make of studies that agree to disagree
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John W. Jackson (2016) conducted an editorial in Attention-deficit/hyperactivity disorder (n=114,647). Methylphenidate vs. Periods of non-use was evaluated on Arrhythmia during the first two months of methylphenidate use (IRR 1.61, 95% CI 1.48 to 1.74). Methylphenidate use was associated with a 61% increased risk of arrhythmia during the first two months of treatment compared to periods of non-use.
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