Highlights preoperative heparin infusion, left ventricular thrombus, and decreased antithrombin III activity as potential causes of heparin resistance before cardiopulmonary bypass.
May guide differential diagnosis of apparent heparin resistance; hypothesis-generating and requires prospective validation before practice change.
Les raisons possibles de resistance apparente a l'heparine sont la perfusion preoperatoire d'heparine, la presence d'un thrombus a l'interieur du ventricule gauche, une diminution de l'activite de l'antithrombine III
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Edward F. Anderson (1986) studied this question.
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