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January 1, 2000DNA ResearchOpen Access

Structurally and Functionally Distinct Mouse Hsp70 Family Members Mot-1 and Mot-2 Proteins are Encoded by Two Alleles

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Abstract

The mouse mortalin proteins Mot-1 and Mot-2 differ by two amino acids in their carboxy-terminus. These proteins are differentially localized in the cell cytoplasm and have contrasting biological activities. The genetic relationship between Mot-1 and Mot-2 was deciphered by mouse family analyses. Mot-1 and Mot-2 segregated in F1 and F2 progeny, providing direct evidence that the two proteins are encoded by two alleles.

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Cite This Study

Sunil C. Kaul (2000) studied this question.

synapsesocial.com/papers/6a926b08333ee566cf962d2d https://doi.org/10.1093/dnares/7.3.229

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