Diffusion/perfusion MR imaging of the brain: from structure to function.

November 1, 1990Radiology

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Key Points

To review the principles and applications of diffusion and perfusion magnetic resonance imaging (MRI) in assessing brain structure, microcirculation, and functional dynamics.
Evaluation of magnetic resonance imaging methodologies utilizing water molecular diffusion and microvascular blood perfusion techniques in neurological imaging.
Synthesis of structural and physiological parameters obtained from advanced neuroimaging sequences.
Diffusion-weighted imaging noninvasively characterizes cellular architecture, tissue integrity, and white matter tract orientation.
Perfusion-weighted imaging measures cerebral blood flow, blood volume, and transit times, enabling direct assessment of tissue viability and functional state.

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Review demonstrates diffusion and perfusion MRI capabilities in brain tissue, highlighting functional and structural mapping.

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Denis Le Bihan (1990) studied this question.

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