Why the study?
Does a higher concentration of ropivacaine (0.75% or 0.50%) improve the onset and duration of anesthesia compared to 0.20% in patients undergoing oral and maxillofacial surgery?
Does a higher concentration of ropivacaine (0.75% or 0.50%) improve the onset and duration of anesthesia compared to 0.20% in patients undergoing oral and maxillofacial surgery?
Ropivacaine 0.75% provides faster onset and longer duration of anesthesia compared to 0.50% and 0.20% concentrations in oral and maxillofacial surgery.
Ropivacaine may offer viable intraoral anesthesia; leaves open comparative efficacy pending randomized trials.
Objective:• Onset of Anesthesia.• Duration of Analgesia and Anesthesia.• Quality of Anesthesia.Methods: This prospective study was conducted in the Department during one year period of June 2012 – 2013 by selectingrandom 75 patients. The included criteria patients were randomly allotted into three groups of 25 each and were randomlyallocated to Group I, Group II and Group III to receive local anesthesia followed by intraoral administration of Ropivacaineand the objective criteria was evaluated.Results: The ANNOVA test was employed to assess the impact of each concentration, and subsequent post hoc testing wasconducted to make group comparisons. Significance was denoted by P values of < 0.05 and highly significant differences byP values of < 0.001. The total mean onset duration for subjective symptoms was 0.75% (1.240.52± minutes), 0.50% (1.801±minute), and 0.20% (2.680.90± minutes). Objective symptoms had onset times of 0.75% (2.660.65± minutes), 0.50% (3.91.32±minutes), and 0.20% (6.841.26± minutes). The onset of these symptoms was notably faster with the 0.75% concentrationcompared to the other two concentrations.Conclusion: The mean anesthesia durations (in hours) were maximum in case of 0.75% (8.021.11± hrs) in comparison toother groups. The mean analgesia durations were maximum in case of 0.75% too (4.493.29± hrs). Nine patients in the 0.75%concentration and eight patients in the 0.50% concentration reported no pain after the procedure, while 25 patients in the 0.20%concentration experienced pain. The duration was significantly different for anesthesia (p=0.001) but not for analgesia (p=0.09)
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Lahiri et al. (2024) studied this question.
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