Why the study?
To provide a comparative evaluation of dexmedetomidine and fentanyl for epidural anaesthesia in lower limb orthopedic surgery.
Does dexmedetomidine improve epidural analgesia compared to fentanyl in patients aged 21-50 undergoing lower limb orthopedic surgery?
Does dexmedetomidine improve epidural analgesia compared to fentanyl in patients aged 21-50 undergoing lower limb orthopedic surgery?
Dexmedetomidine provides better epidural analgesia with faster onset and prolonged post-operative pain relief compared to fentanyl in lower limb orthopedic surgery.
Demographic similarity supports trial validity; leaves open comparative efficacy of dexmedetomidine versus fentanyl for epidural anesthesia.
Aim:Comparative evaluation of dexmedetomidine and fentanyl for epidural anaesthesia in lower limb orthopedic surgery. Methods: Patients undergoing lower limb orthopaedic surgery aged between 21 to 50 years. For statistical analysis data were entered into a Microsoft excel spreadsheet and then analyzed by SPSS (version 27.0; SPSS Inc., Chicago, IL, USA) and GraphPad Prism version 5. Result: Difference of mean age with both groups was not statistically signicant (p=0.217). Difference of mean duration of surgery with both groups was not statistically signicant (p<0.001).Difference of mean onset time of sensory block (at T10) with both groups was statistically signicant (p<0.001). Difference of mean time of onset of moter block with both groups was statistically signicant (p<0.001). Conclusion: Dexmedetomidine seems to be a better alternative to fentanyl for epidural anaesthesia because of intense analgesia, better quality of motor block and prolong post op analgesia, along with higher sedation scores.
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Kumar et al. (2021) studied this question.
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