The addition of increasing levels of phytohemagglutinin to amethopterin-treated cultures of human lymphocytes results in the induction of DNA synthesis which can be measured by the incorporation of exogenous radioactive thymidine. The graded nature of this response permits the assay of mitogenic activity of such preparations as well as the assessment of antimitogenic factors in sera.
No takes yet. Share an insight, caveat, or question.
Tormey et al. (1965) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: