Why the study?
Cutaneous angiosarcoma can resemble benign lesions, leading to diagnostic delays and poor outcomes, prompting an analysis of its atypical clinical forms.
Clinicians should be aware of atypical presentations of cutaneous angiosarcoma to prevent delays in diagnosis and treatment.
Clinicians should suspect CAS in atypical head/neck lesions to avoid delay; review leaves open validated diagnostic algorithms.
Cutaneous angiosarcoma (CAS) is an aggressive tumour of vascular or lymphatic origin. Although relatively rare, it needs to be recognized and treated early. CAS typically arises on the head or neck as a bruise or raised purplish-red papule or plaque. However, it can sometimes resemble a benign skin lesion, leading to delay in diagnosis and consequent poor patient outcome. CAS may be mistaken for inflammatory, autoimmune or infectious disease, or for a benign skin tumour or post-traumatic lesion. We analyse the atypical clinical forms of this aggressive tumour and review the literature.
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Kostaki et al. (2022) studied this question.
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