Viral infection may be an important and underrecognized cause of pericarditis in chronically dialyzed patients, distinct from uremic pericarditis.
May support viral serology in dialysis pericarditis; hypothesis-generating and leaves open whether testing changes management.
Four patients with end-stage renal disease in whom pericarditis developed while they received intermittent hemodialysis therapy were evaluated for viral infection. We found high or rising serum antibody titers to influenza virus A (three patients) and coxsackievirus B (one patient). Cardiac tamponade occurred in three patients, requiring pericardiectomy in two; each patient eventually recovered. Viral pericarditis may be an important cause of "uremic" pericarditis in chronically dialyzed patients.
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Enayatolla Osanloo (1979) studied this question.
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