Characterisation of the HLA‐DPA1*01:194:01:02 Allele by Next‐Generation Sequencing

Q: What does this research mean for the field?

A novel HLA-DPA1 allele, HLA-DPA1*01:194:01:02, exists and was identified in a Canadian liver transplant candidate of European descent. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

Abubaker M. E. Sidahmed; Arpit Sharma; Lingyi Chen; David Beaune; Lakshman Gunaratnam

doi:10.1111/tan.70952

August 27, 2026HLA

Characterisation of the HLA‐DPA1*01:194:01:02 Allele by Next‐Generation Sequencing

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Key Points

To identify and characterize the novel HLA-DPA1*01:194:01:02 allele.
Performed high-resolution next-generation sequencing on genomic DNA from a Canadian liver transplant candidate of European descent.
Identified and officially characterized the novel human leukocyte antigen allele designated as HLA-DPA1*01:194:01:02.

Implication

Genomic sequencing reveals a novel HLA-DPA1*01:194:01:02 allele in a liver transplant candidate, highlighting expanding genetic diversity for clinical histocompatibility.

Abstract

Novel HLA-DPA1*01:194:01:02 allele identified in Canadian liver transplant candidate of European descent by next-generation sequencing.

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Cite This Study

Sidahmed et al. (2026) studied this question.

synapsesocial.com/papers/6a9299338e5d7d1fc0c1100e https://doi.org/10.1111/tan.70952

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Characterisation of the HLA‐DPA1*01:194:01:02 Allele by Next‐Generation Sequencing

Key Points

Implication

Abstract

Discussion

Cite This Study

Characterisation of the HLA‐DPA1*01:194:01:02 Allele by Next‐Generation Sequencing

Key Points

Implication

Abstract

Discussion

Cite This Study

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