Enzymatic synthesis of diadenosine 5′, 5‴-P 1 , P 4 -tetraphosphate (Ap 4 A) analogues by stress protein LysU

Preparative synthesis of analogues of the biologically important molecule diadenosine 5′, 5‴-P1, P4-tetraphosphate (Ap4A) is achieved in good yield by enzyme catalysis using the stress protein LysU.