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August 29, 2026Developmental PsychobiologyOpen Access

Linking Brain, Heart, and Behavior in Children: Frontal Electroencephalogram Activity, Respiratory Sinus Arrhythmia, and Internalizing Behaviors

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Why the study?

Phasic changes in overall frontal EEG alpha activity and respiratory sinus arrhythmia independently associate with internalizing behaviors in children, but whether their interaction predicts internalizing behaviors was unknown.

Population

152 typically developing children (M age = 7.82 years, 73 girls, 81.6% White)

Comparison

Changes in overall FAA and RSA from baseline to stress induction

Design

Observational physiological study

Key result

Increases in frontal EEG alpha activity during stress were associated with greater internalizing behaviors in children who also exhibited a decrease in respiratory sinus arrhythmia.

Authors

YYYoure YangKPKristie L. PooleLSLouis A. Schmidt

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Overview

Phasic FAA/RSA changes may index child emotion dysregulation; leaves open prospective prediction of internalizing behaviors or intervention targets.

Key Points

  • To determine whether the interaction between changes in frontal electroencephalogram alpha activity (FAA) and respiratory sinus arrhythmia (RSA) from baseline to stress predicts internalizing behaviors in children.
  • Assessed 152 typically developing children (mean age = 7.82 years, 73 girls, 81.6% White).
  • Measured shifts in central (overall FAA) and peripheral (RSA) physiological activity from resting baseline to an acute stress induction.
  • A significant interaction emerged between baseline-to-stress changes in FAA and RSA in predicting internalizing behaviors.
  • Increases in FAA coupled with decreases in RSA predicted greater internalizing behaviors, whereas FAA increases alongside RSA increases were associated with fewer internalizing behaviors.

Study Design

Type

Observational (n=152)

Structured PICO

P
Population
152 typically developing children (mean age 7.82 years, 48% female) assessed for physiological responses to stress induction and internalizing behaviors.
E
Exposure
Stress induction (assessing changes in frontal EEG alpha activity and respiratory sinus arrhythmia)
O
Outcome
Internalizing behaviors

Measures indexing central and peripheral nervous system activity (FAA and RSA) may jointly influence stress regulation and contribute to vulnerability to internalizing behaviors in middle childhood.

Cite This Study

Yang et al. (2026) conducted an observational in Internalizing behaviors (n=152). Changes in frontal EEG alpha activity (FAA) and respiratory sinus arrhythmia (RSA) was evaluated on Internalizing behaviors. Increases in frontal EEG alpha activity during stress were associated with greater internalizing behaviors in children who also exhibited a decrease in respiratory sinus arrhythmia.

synapsesocial.com/papers/6a9299bb8e5d7d1fc0c11d52https://doi.org/10.1002/dev.70192
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