Why the study?
Cytomorphological features of alveolar rhabdomyosarcoma on serous effusions have not been well documented despite its well-known histopathologic and immunohistochemical findings.
Highlights the cytomorphological features and diagnostic difficulties of metastatic alveolar rhabdomyosarcoma in pericardial fluid.
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May aid cytological recognition of metastatic rhabdomyosarcoma in pericardial fluid; leaves open validation in larger series.
Alveolar rhabdomyosarcoma (ARMS) commonly occurring in children and adolescents, is a rare and aggressive soft tissue malignancy demonstrating rapid growth and dissemination. Although their histopathologic and immunohistochemical findings are well known, cytomorphological features on serous effusions have not been well documented. A case of metastatic rhabdomyosarcoma diagnosed on cytological examination of the pericardial fluid cytology and discuss the diagnostic difficulties that were encountered in this case has been presented.
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Straccia et al. (2021) studied this question.
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