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Abstract 1. Previous findings disproving the identity of liver aldolase (1‐phosphofructaldolase) and cristalline muscle aldolase (1,6‐diphosphofructaldolase) have been confirmed and extended. Highly purified muscle aldolase does not split fructose‐1‐phosphate even at concentrations of 0,5 mg enzyme/ml. (Optical method: oxydation of (DPN)H2 in the presence of phosphoglycerol dehydrogenase). High purity of the enzyme is essential to prove its specificity for fructose diphosphate.
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Leuthardt et al. (1954) studied this question.
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