PARTITION OF VITAMIN A 399 compared with the figures from two control cows receiving exactly the same dietary treatment.2. The pituitary preparation increased the vitamin A alcohol output in the milk whether greenstuff was present in the diet or not.3. When there was no greenstuff in the diet the output of vitamin A alcohol in the milk increased and this increase was enhanced in the hormonally treated cows.4. In the absence of green food there was no vitamin A ester in the blood and yet the output of vitamin A ester in the milk was also increased by the hormone preparation so that the hormonal treat- ment increased the rate of esterification of vitamin A by the mammary gland.5. When greenstuff was present in the diet the blood contained vitamin A ester in amounts which were increased by the hormonal treatment.6.The hormonal treatment increased the vitamin A alcohol in the blood serum whether or not there was greenstuff in the diet.7. The results lend weight to the hypothesis that, like thyroxine, the hormone preparation accelerated the mobilization of hepatic reserves as vitamin A alcohol into the blood and hence into the milk as alcohol and ester.There was also some evidence that, like thyroxine, the hornone preparation accelerated the transformation of dietary carotene into vitamin A in the guit.8. The results provided evidence for the hypothesis that vitamin A ester in the milk could, when the diet contained carotene, have either a hepatic or a dietary origin according as it came from the alcohol or the ester of vitamin A circulating in the blood.The authors wish to thank Mis P. McGuigan and Miss S.
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Saroja et al. (1955) studied this question.
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