Solitary plexiform neurofibroma of the malar region: A rare and unusual presentation

Plexiform neurofibromas are benign tumors of the peripheral nerves and are usually considered pathognomonic of neurofibromatosis type 1. We discuss the case of a young male patient presenting with a solitary mass over the malar region. Pathologic examination revealed a plexiform neurofibroma of the infraorbital nerve. No other signs or symptoms of neurofibromatosis were identified. Although rare, plexiform neurofibromas may rarely occur as solitary lesions not associated with the neurofibromatosis spectrum. It can be seen in unusual anatomic location such as the malar region and should be considered in the diagnosis of soft tissue facial tumors.