Key result
A young girl suffered sudden death from an aortic dissection complicating a neck paraganglioma, with postmortem blood metanephrines 100 times higher than normal.
Case Report (n=1)
This case highlights the importance of considering paraganglioma in cases of sudden hypertensive complications, such as aortic dissection, especially among young people.
May prompt paraganglioma consideration in young aortic dissection; hypothesis-generating and leaves open need for validation.
Neck paragangliomas are relatively rare neuroendocrine nonsecretory tumors. They are mainly observed among adults and are often asymptomatic, causing a frequent delay in diagnosis. In pediatric cases, neck paragangliomas can be associated with adrenergic symptoms that may lead to complications.A report of a sudden death due to a carotid paraganglioma in a young girl is reported. Autopsy revealed a thoracic arotic dissection and a 4-cm jugulocarotidian mass in the absence of traumatic injuries. Histology showed no evidence of underlying aortic disease, including signs of Marfan syndrome, and a paraganglioma. Postmortem biochemistry analysis showed blood metanephrines levels 100 times higher than normal range. The cause of death was an aortic dissection complicating a neck paraganglioma. The manner of death was concluded as natural.Our case highlighted the importance for forensic pathologist to consider the diagnosis of paraganglioma in case of sudden hypertensive complications, especially among young people.
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Abderrahim et al. (2020) conducted a case report in Neck paraganglioma (n=1). Neck paraganglioma was evaluated on Sudden death. A young girl suffered sudden death from an aortic dissection complicating a neck paraganglioma, with postmortem blood metanephrines 100 times higher than normal.
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