Motor neurone disease is one of the most common neurodegenerative diseases of adult onset. Currently, there is no treatment that substantially slows disease progression, and average survival from the start of symptoms is only about three years. As this article discusses, however, new understanding of disease pathogenesis is suggesting the way toward more effective neuroprotective treatments aimed at slowing or arresting injury to motor neurones.
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Pamela J. Shaw (1999) studied this question.
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