Answers are grounded in this paper and cite their sources.
Distinct signal transduction cascades comprised of at least three proteinkinases mediate cellular proliferation and differentiation, growth arrest, and programmed cell death. These cytosolic enzymes relay extracellular signals from cell surface to nucleus, leading to changes in gene expression. Signaling components of these cascades offer new possibilities for therapeutic strategies in tumorigenesis, inflammatory diseases, immunopotentiation, wound healing, and regeneration.
No takes yet. Share an insight, caveat, or question.
JT Neary (1997) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: