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was preferentially hyperactivated by combinatorial treatment. ceRNA analysis predicted potential sponging of miR-29, miR-21, and miR-155, which may derepress BMP signaling and extracellular matrix remodeling. QMR reshapes the ARPE-19 non-coding transcriptome and enables a non-additive transcriptomic response to secretome co-treatment. The QMR-secretome-circRNA axis identifies candidate non-coding biomarkers and therapeutic targets for retinal regeneration.
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Alibrandi et al. (2026) studied this question.
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