Key result
Spinal cord stimulation provided significant pain relief and positive limb salvage outcomes over time in patients with peripheral arterial disease, critical limb ischemia, and peripheral vascular disease.
Why the study?
The study was conducted to evaluate the efficacy and safety of spinal cord stimulation for pain relief and limb salvage in patients with peripheral arterial disease.
Does spinal cord stimulation improve pain relief and limb salvage in patients with peripheral arterial disease?
Systematic Review (n=1,079)
Does spinal cord stimulation improve pain relief and limb salvage in patients with peripheral arterial disease?
Spinal cord stimulation appears to be an effective intervention for providing significant pain relief and improving limb salvage in patients with peripheral arterial disease and critical limb ischemia.
Answers are grounded in this paper and cite their sources.
Supports SCS consideration in refractory CLI; confirms sustained benefits via systematic evidence synthesis.
This systematic review evaluated the efficacy and safety of Spinal Cord Stimulation (SCS) in patients with Peripheral Arterial Disease (PAD). The study analysed pain relief and limb salvage outcomes by systematically reviewing relevant literature published in the past ten years. Out of 191 records screened, a total of 10 studies were included, involving 1,079 patients. The selected studies used various research designs and assessed either pain levels or limb salvage, or both.
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Salah Rustom (2023) conducted a systematic review in Peripheral Arterial Disease (PAD), Critical Limb Ischemia (CLI), Peripheral Vascular Disease (PVD) (n=1,079). Spinal Cord Stimulation (SCS) vs. Standard conservative treatment or baseline was evaluated on Pain relief (Visual Analog Scale scores) and limb salvage outcomes. Spinal cord stimulation provided significant pain relief and positive limb salvage outcomes over time in patients with peripheral arterial disease, critical limb ischemia, and peripheral vascular disease.
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