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A random sequential adsorption model for the adsorption of proteins to surfaces functionalized with poly(ethylene oxide)/poly(ethylene glycol) at a range of molecular weights and grafting densities is presented. An excellent fit of the model predictions to experimental results suggests that the random arrangement of polymer chains leading to polymer-free “bald” spots is a critical factor in primary protein adsorption.
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Katira et al. (2008) studied this question.
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