Part 7: Adult Advanced Cardiovascular Life Support

Management of Cardiac ArrestStandard-dose epinephrine (1 mg every 3 to 5 minutes) may be reasonable for patients in cardiac arrest (Class IIb, LOE B-R).updated for 2015 2015 Management of Cardiac Arrest High-dose epinephrine is not recommended for routine use in cardiac arrest (Class III: No Benefit, LOE B-R).new for 2015 2015 Management of Cardiac Arrest Vasopressin offers no advantage as a substitute for epinephrine in cardiac arrest (Class IIb, LOE B-R).updated for 2015 2015 Management of Cardiac Arrest Vasopressin in combination with epinephrine offers no advantage as a substitute for standarddose epinephrine in cardiac arrest (Class IIb, LOE B-R).new for 2015 2015 Management of Cardiac Arrest It may be reasonable to administer epinephrine as soon as feasible after the onset of cardiac arrest due to an initial nonshockable rhythm (Class IIb, LOE C-LD).updated for 2015 2015 Management of Cardiac Arrest In IHCA, the combination of intra-arrest vasopressin, epinephrine, and methylprednisolone and post-arrest hydrocortisone as described by Mentzelopoulos et al may be considered; however, further studies are needed before recommending the routine use of this therapeutic strategy (Class IIb, LOE C-LD).new for 2015 2015 Management of Cardiac Arrest For patients with OHCA, use of steroids during CPR is of uncertain benefit (Class IIb, LOE C-LD).new for 2015 2015 Management of Cardiac Arrest