Presently accepted methods for calculating the expected response for combinations of agents such as herbicides or other growth regulators from the responses of individual agents can lead to unacceptable results. This may be true even if responses within the linear region of the individual response curves are used in such calculations. A solution to this problem is to assign parameters to response curves of individual agents and to define the expected response function for combinations of agents by the weighted algebraic means of these parameters.
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F. H. A. Rummens (1975) studied this question.
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