Key result
A mathematical model treating the heart as a thick cylindrical shell was developed to compute regional stresses and strains through the left ventricular wall in normal and diseased hearts.
Answers are grounded in this paper and cite their sources.
This computational modeling approach provides a method to determine in vivo material constants of the heart, potentially aiding in the understanding of cardiac adaptation and earlier diagnosis of heart disease.
In this paper, a method is developed to determine the material constants of normal and diseased human hearts in vivo. With these material constants, one can compute regional stresses and strains through the left ventricular (LV) wall. This knowledge provides a better understanding of the heart adaptation process and may lead to earlier diagnosis of heart disease. It also may enable earlier treatment of heart disease, and evaluation of the efficacy of treatments for it. The heart is modeled as a thick cylindrical shell and large deformation theory, incorporating residual stresses is employed to compute the regional stresses and strains through the LV wall. These stresses and strains at the end diastolic state for the normal, hypertensive and congestive heart failure cases are presented. The average circumferential stress is also computed at the end systolic state for these cases.
No takes yet. Share an insight, caveat, or question.
Chaudhry et al. (2002) studied Hypertension and congestive heart failure. Mathematical modeling of the heart as a thick cylindrical shell was evaluated on Regional stresses and strains through the left ventricular wall. A mathematical model treating the heart as a thick cylindrical shell was developed to compute regional stresses and strains through the left ventricular wall in normal and diseased hearts.
Synapse has enriched 10 related papers. Consider them for comparative context: