The effect of X-radiation on the spermatogenesis of the Guinea-pig

The effect of X-rays on tissues and cells has been the subject of study by many observers, dating back to the time when Leopold Freund, of Vienna, burnt the first patient. We were led to study this problem merely from the hope that the more modern cytological techniques might reveal some new facts with reference to the mystery of the effect of X-rays on the cell. Moreover, we hoped to collect some interesting facts about the mechanism of sperm formation. We are grateful to the British Medical Association for a grant in aid of this work; to Dr. Bethel Solomons, the Master, and Dr. M. MacDonagh, the Radiologist of the Rotunda Hospital, for the use of the hospital X-ray plant and to many people for the loan of literature. One of us (S. W.) has received a Research Scholarship from the Irish Free State Government, whom we most cordially thank.