Key result
A bibliometric analysis of the top 100 most cited articles on PPAR-γ found the most cited article had 2,571 citations, with Harvard University publishing the highest number of articles.
Why the study?
This study aimed to identify the top 100 most influential articles in the field of PPAR-gamma to render trends providing insight into the history and potential future directions of the field.
Answers are grounded in this paper and cite their sources.
This bibliometric analysis identifies the top 100 most influential articles on PPAR-γ, highlighting key trends, institutions, and authors to guide future research directions.
BACKGROUND: PPAR-γ is one of three members of the PPAR group of the nuclear receptor superfamily and plays an important regulatory role as a ligand-dependent transcription factor. OBJECTIVE: This study aimed to identify the top 100 most influential articles in the field of PPAR-γ. We hypothesized that a bibliometric and scientometric analysis of the PPAR-γ research field could render trends that provide researchers and funding agencies valuable insight into the history of the field, and potential future directions. METHODS: A literature search of publications was carried out using the Web of Science (WOS) and Scopus database based on specific subject words on September 11, 2023. Articles were listed in descending order of the number of citations. Statistical analysis was performed on the data of the top 100 cited articles in terms of year of publication, journal, research direction, institution, author, and country. Meanwhile, co-authorship networks and co-citation networks were constructed by using VOSviewer software, and keywords were analyzed for co-occurrence. RESULTS: A total of 9,456 articles regarding PPAR-γ were identified and analyzed based on the WOS database, and the top 100 cited articles in the field of PPAR-γ were ranked by citation. The most cited article was published in 1998, with 2,571 citations and a density of 102.80 citations/ year. Of the 100 articles, Harvard University was the institution with the highest number of articles published. Spiegelman, B. M. was the author with the highest number of articles published. Using the VOSviewer software, we found that the most used keywords were geneexpression, activated receptor-gamma, and adipocyte differentiation. PPAR-γ, one of the most widely studied transcription factors, is an important drug target for many diseases. Therefore, screening for small molecule compounds targeting PPAR-γ remains of great value. CONCLUSION: The present study identified the top 100 most influential articles in the field of PPAR-γ, which help global researchers to better understand research perspectives and develop future research directions of PPAR-γ.
No takes yet. Share an insight, caveat, or question.
Wu et al. (2024) studied PPAR-γ research (n=100). Bibliometric analysis of PPAR-γ articles was evaluated on Citation count and bibliometric characteristics. A bibliometric analysis of the top 100 most cited articles on PPAR-γ found the most cited article had 2,571 citations, with Harvard University publishing the highest number of articles.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: