The pituitary fossa in Cushing's syndrome. A retrospective analysis of 93 patients

A retrospective analysis of the pituitary fossa in 93 patients with Cushing's syndrome is presented. Radiological evidence of a pituitary tumour was found in 20 of 86 patients with pituitary-dependent disease (23%). In 11 of the 20 patients, the diagnosis depended on analysis of lateral tomograms. None of the seven patients with disease which was not pituitary-dependent had evidence of an abnormal sella. One of 20 controls without known endocrine disease had an abnormal sella.