Key result
A 27-year-old man with right atrium angiosarcoma and multiple metastases died after 27 days due to hemorrhage from brain metastases.
Why the study?
Cardiac angiosarcoma has a dismal prognosis and is difficult to diagnose due to nonspecific imaging and inaccurate biopsies, with hemorrhagic metastases potentially proving fatal.
Case Report (n=1)
Brain metastases from cardiac angiosarcoma can cause fatal hemorrhage, suggesting urgent radiotherapy should be considered if suspected on imaging.
Raises caution for fatal brain metastasis hemorrhage in cardiac angiosarcoma; leaves open radiotherapy's role pending prospective data.
Cardiac angiosarcoma is a malignant tumor derived from vascular endothelium with a dismal prognosis. The imaging findings of cardiac angiosarcoma are nonspecific and endomyocardial and pericardial biopsies have insufficient accuracy. For these reasons, the diagnosis is sometimes difficult. Primary and metastatic tumors tend to bleed easily, causing hemoptysis and neurological symptoms. Brain metastases are not often known to be fatal when they cause hemorrhage. We report a 27-year-old man diagnosed with right atrium angiosarcoma, with metastases in the lung, brain, and bone. The patient had only respiratory symptoms at the first visit and did not show any symptoms derived from brain metastases yet died after 27 days due to hemorrhage from brain metastases. If brain metastasis from angiosarcoma is suspected based on imaging findings, urgent radiotherapy should be considered before histological examination for a definitive diagnosis.
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Yamashita et al. (2023) conducted a case report in Cardiac angiosarcoma (n=1). Cardiac angiosarcoma was evaluated on Death. A 27-year-old man with right atrium angiosarcoma and multiple metastases died after 27 days due to hemorrhage from brain metastases.
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