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This investigation has defined a relationship that glucose concentration and flow rate have upon the rate of glucose uptake by the resting perfused rat hindlimb. The glucose uptake rate is linearly related to the perfusate glucose concentration within the range of glucose concentration studied (50-400 mg%). It has also been determined that glucose uptake rate is hyperbolically related to the perfusate flow rate. It appears as though the glucose uptake rate is flow limited for rat skeletal muscle at rest.
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Grubb et al. (1977) studied this question.
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