Answers are grounded in this paper and cite their sources.
Monosodium urate (MSU), calcium pyrophosphate dihydrate (CPPD) and basic calcium phosphate (BCP) crystals deposit in joints and surrounding tissues causing acute inflammation and chronic cartilage damage. A number of endogenous substances and physicochemical conditions affect their precipitation, growth and even dissolution, regulating their metabolism and inflammatory activity. We review how MSU and calcium crystals form within the joints and the various factor which regulate their formation.
No takes yet. Share an insight, caveat, or question.
Oliviero et al. (2012) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: