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Atrial natriuretic peptide (ANP) affects cardiac electrophysiology, including heart rate and refractory period, through autonomic interactions and direct actions on cardiac ion currents.
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This review summarizes the autonomic and direct effects of atrial natriuretic peptide on cardiac electrophysiology and ion currents.
Atrial natriuretic peptide (ANP) has varied effects on cardiac electrophysiologic parameters including heart rate, intraatrial conduction time, and refractory period. ANP's vagoexcitatory and sympathoinhibitory actions as well as its direct actions on cardiac ion currents may be responsible for some of these effects. This review discusses the role of ANP in cardiac electrophysiology, its interactions with the autonomic nervous system and baroreceptor reflex, and its effects on cardiac ion currents.
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Clemo et al. (1996) conducted a review in Cardiac electrophysiology. Atrial natriuretic peptide (ANP) was evaluated. Atrial natriuretic peptide (ANP) affects cardiac electrophysiology, including heart rate and refractory period, through autonomic interactions and direct actions on cardiac ion currents.
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